Modular Access to Chiral α-(Hetero)aryl Amines via Ni/Photoredox-Catalyzed Enantioselective Cross-Coupling

Autor:	Xiaomin Shu, De Zhong, Yanmei Lin, Xiao Qin, Haohua Huo
Rok vydání:	2022
Předmět:	Colloid and Surface Chemistry Chlorides Nickel Stereoisomerism General Chemistry Amines Chlorine Biochemistry Catalysis
Zdroj:	Journal of the American Chemical Society. 144:8797-8806
ISSN:	1520-5126 0002-7863
DOI:	10.1021/jacs.2c02795
Popis:	Chiral α-aryl N-heterocycles are commonly found in natural products, pharmaceutical agents, and chiral catalysts but remain challenging to access via asymmetric catalysis. Herein, we report a general and modular approach for the direct enantioselective α-arylation of saturated azacycles and acyclic
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5ce0a263c8445c227a716f593ba912b https://doi.org/10.1021/jacs.2c02795 Zobrazit plný text záznamu