Similar bleeding phenotype in young children with haemophilia A or B: a cohort study
| Autor: | HERVE CHAMBOST, Johanna G. Van der Bom, Angelo Claudio Molinari, Beatrice Nolan, Samantha Gouw, Chris Van Geet, Johannes Oldenburg, Maria Elisa Mancuso |
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| Přispěvatelé: | AII - Amsterdam institute for Infection and Immunity, Paediatric Infectious Diseases / Rheumatology / Immunology |
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty congenital hereditary and neonatal diseases and abnormalities Genotype Haemophilia A Hemorrhage macromolecular substances Hemophilia A Haemophilia Hemophilia B Severity of Illness Index Cohort Studies Factor IX hemic and lymphatic diseases Severity of illness medicine Humans Haemophilia B Registries Child Genetics (clinical) Clotting factor Factor VIII business.industry Infant Newborn Infant Hematology General Medicine Bleed medicine.disease Phenotype Child Preschool Mutation Female business medicine.drug Cohort study |
| Zdroj: | Haemophilia, 20(6), 747-755. Wiley-Blackwell Clausen, N, Petrini, P, Claeyssens-Donadel, S, Gouw, S C, Liesner, R & PedNet and Research of Determinants of Inhibitor development (RODIN) Study Group 2014, ' Similar bleeding phenotype in young children with haemophilia A or B : a cohort study ', Haemophilia Online, vol. 20, no. 6, pp. 747-55 . https://doi.org/10.1111/hae.12470 |
| ISSN: | 1351-8216 |
| DOI: | 10.1111/hae.12470 |
| Popis: | The bleeding phenotype has been suggested to differ between haemophilia A and B. More knowledge on the bleeding phenotype at initiation of treatment is important to optimize patient care. The aim of this study was to investigate the severity of the bleeding phenotype and the variation in bleeding in children with severe or moderate haemophilia A and B. Consecutive, previously untreated patients with severe or moderate haemophilia A and B (factor VIII or IX activity |
| Databáze: | OpenAIRE |
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