Concept of experimental preparation for treating dentin hypersensitivity
| Autor: | Mirosław Gibas, Małgorzata Skucha-Nowak, Marta Tanasiewicz, Agnieszka Machorowska-Pieniążek, Henryk Twardawa |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Dental practice
Biocompatibility Dentistry 02 engineering and technology Dental adhesive monomer Optical microscopy Nuclear magnetic resonance 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine stomatognathic system medicine Dentin Desensitizer Statistical analysis business.industry 030206 dentistry General Medicine 021001 nanoscience & nanotechnology medicine.disease stomatognathic diseases Dentin desensitizer Monomer chemistry Dentin hypersensitivity Medicine Dentinal hypersensitivity Adhesive Tooth Tissue 0210 nano-technology business Research Article |
| Zdroj: | Open Medicine Open Medicine, Vol 11, Iss 1, Pp 387-393 (2016) |
| ISSN: | 2391-5463 2016-0070 |
| Popis: | Background Dentinal hypersensitivity (DH) is a diagnostic and therapeutic problem that is now appearing more frequently in modern dentistry. The aim of this work was to elaborate formulation of a new, original desensitizing preparation with prolonged action based on the knowledge of similar commercializations and to compare their performance in vitro. Methodology The analyses were performed with the aid of NMR spectroscopy. The experimental and commercial preparations were examined in vitro after thermocycling on human teeth by optical microscopy. The presence of the material on tooth tissue, its ability to penetrate into the tooth structure and its layer thickness were subjected to statistical analysis. Results A detailed knowledge on composition of commercial material was achieved from spectroscopic measurements. A new adhesive monomer was synthesized and incorporated into an experimental desensitizing formulation. The new monomer appeared to have comparable performance to the commercial one when regarding the affinity to tooth tissue and resistance to thermocycling. Conclusions The experimental formulation comprising a new adhesive monomer seems to be promising and could be applied in dental practice providing that biocompatibility is satisfactory. |
| Databáze: | OpenAIRE |
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