Diabetic Ketoacidosis and Hyperglycemic Hyperosmolar State
Autor: | Andrew Drexler, Jelena Maletkovic |
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Rok vydání: | 2013 |
Předmět: |
medicine.medical_specialty
Pediatrics endocrine system diseases Diabetic ketoacidosis business.industry Endocrinology Diabetes and Metabolism Insulin medicine.medical_treatment Water-Electrolyte Imbalance nutritional and metabolic diseases Hyperosmolar state medicine.disease Diabetic Ketoacidosis Surgery Endocrinology Hyperglycemia Diabetes mellitus Epidemiology Life expectancy Fluid Therapy Humans Hypoglycemic Agents Medicine business |
Zdroj: | Endocrinology and Metabolism Clinics of North America. 42:677-695 |
ISSN: | 0889-8529 |
DOI: | 10.1016/j.ecl.2013.07.001 |
Popis: | Diabetic ketoacidosis (DKA) and the hyperglycemic hyperosmolar state (HHS) are potentially fatal hyperglycemic crises that occur as acute complications of uncontrolled diabetes mellitus. The authors provide a review of the current epidemiology, precipitating factors, pathogenesis, clinical presentation, evaluation, and treatment of DKA and HHS. The discovery of insulin in 1921 changed the life expectancy of patients with diabetes mellitus dramatically. Today, almost a century later, DKA and HHS remain significant causes of morbidity and mortality across different countries, ages, races, and socioeconomic groups and a significant economic burden for society. |
Databáze: | OpenAIRE |
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