Intraplacental retinol distribution
| Autor: | Ana Paula Pereira Thiapó de Lima, Paula Leite, Alexandre Gonçalves Soares, Paulo Roberto Borges de Souza Júnior, Maria do Carmo Leal, Rejane Andréa Ramalho, Hernando Flores, Mirian Martins Gomes, Cláudia Saunders |
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| Rok vydání: | 2006 |
| Předmět: |
Vitamin
Adult medicine.medical_specialty Adolescent Placenta Physiology Nutritional Status Biology Specimen Handling chemistry.chemical_compound Fetal membrane Pregnancy Reference Values Internal medicine medicine Distribution (pharmacology) Humans Vitamin A Maternal-Fetal Exchange Subclinical infection Fetus Postpartum Period Retinol medicine.disease Vitamin A deficiency Endocrinology medicine.anatomical_structure chemistry Female Food Science |
| Zdroj: | International journal of food sciences and nutrition. 56(8) |
| ISSN: | 0963-7486 |
| Popis: | With the objective of evaluating intraplacental vitamin A distribution, 234 placental samples were collected, corresponding to six samples from each of the placentas analyzed: two from the lateral maternal portion, one from the central maternal portion, two from the lateral fetal portion, and one from the central fetal portion. Samples were obtained from 39 adult puerperal mothers with low-risk pregnancies, without vitamin A deficiency or night blindness. Retinol content determination was achieved through spectrophotometry. Retinol values obtained for each region were correlated with the most probable value for each placenta (P < 0.001). Despite differences in retinol content between samples, statistical data analysis showed that intra-tissue variation had no influence on the conversion of data into information. Consequently, any portion of the placenta may be used for retinol level determination purposes, due to the correlation between all portions and the most probable value. The findings of the present study represent an advance for surveys intending to incorporate the collection and dosage of placental vitamin A levels into their analyses, thus increasing the arsenal of pre-pathological or subclinical vitamin A deficiency markers, which can allow for earlier intervention on the maternal-infant group. |
| Databáze: | OpenAIRE |
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