Two cases of renal cell cancer during immunobiologic therapy for psoriasis
Autor: | João Carlos Regazzi Avelleira, Monique Samy Pamplona Mafort, Paula Regazzi de Gusmão, Luiza Ferreira Vieira d'Almeida, Fabiana Palmieri Zarur |
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Jazyk: | angličtina |
Rok vydání: | 2014 |
Předmět: |
Adult
Male medicine.medical_specialty MEDLINE Dermatology Receptors Tumor Necrosis Factor Etanercept Risk Factors Psoriasis medicine Carcinoma Humans Immunologic Factors Neoplasm Biological therapy Carcinoma Renal Cell Aged Tumor Necrosis Factor-alpha business.industry Communication Antibodies Monoclonal Middle Aged medicine.disease Infliximab Surgery Treatment Outcome Immunoglobulin G RL1-803 Cell cancer Dermatologic Agents Complication business Kidney neoplasms medicine.drug |
Zdroj: | Anais Brasileiros de Dermatologia, Volume: 89, Issue: 6, Pages: 1017-1018, Published: DEC 2014 Anais Brasileiros de Dermatologia, Vol 89, Iss 6, Pp 1017-1018 (2014) Anais Brasileiros de Dermatologia Anais Brasileiros de Dermatologia v.89 n.6 2014 Anais brasileiros de dermatologia Sociedade Brasileira de Dermatologia (SBD) instacron:SBD |
Popis: | Immunobiologic therapy is indicated for severe forms of psoriasis, resistant to conventional therapy. There is growing concern about their safety profile and possible association with cancer development. This article documents two cases of renal cell cancer during treatment with biologic therapy, reviewing what is described in the literature . The risk of solid tumors as a complication of using TNF-alpha inhibitors is controversial. No conclusion can be drawn from the data in the literature, however, we believe that special attention should be given to those with known risk factors for a specific neoplasm. |
Databáze: | OpenAIRE |
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