A Case of Primary Hyperparathyroidism due to Intrathyroidal Parathyroid Cyst
| Autor: | Omer Alici, Aysu Basak Ozbalci, Gulhan Duman, Yavuz Yalcin, Gultekin Ozan Kucuk, Turkan Mete, Recep Aktimur |
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| Rok vydání: | 2014 |
| Předmět: |
Pathology
medicine.medical_specialty lcsh:RC648-665 endocrine system diseases medicine.diagnostic_test business.industry Endocrinology Diabetes and Metabolism Thyroid Case Report Nodule (medicine) medicine.disease Scintigraphy lcsh:Diseases of the endocrine glands. Clinical endocrinology Intrathyroidal Parathyroid Lesion medicine.anatomical_structure medicine Cyst medicine.symptom business hormones hormone substitutes and hormone antagonists Primary hyperparathyroidism Parathyroid adenoma |
| Zdroj: | Case Reports in Endocrinology Case Reports in Endocrinology, Vol 2014 (2014) |
| ISSN: | 2090-651X 2090-6501 |
| DOI: | 10.1155/2014/213283 |
| Popis: | Parathyroid cysts constitute 0.08–3.41% of all parathyroid masses. Intrathyroidal parathyroid cysts, however, are rare conditions with only a few cases being reported. Most of the parathyroid cysts are found to be nonfunctional and functional cysts are generally thought to be due to cystic degeneration of parathyroid adenomas. A cystic, smooth contoured lesion of 24 × 19 × 16 mm was observed in left thyroid lobe of a 76-year-old woman during ultrasonography which was performed as routine workup for primary hyperparathyroidism. It was defined as a cystic thyroid nodule at first. Tc99msestamibi scintigraphy was performed to see any parathyroid lesions, but no radioactive uptake was observed. Intact parathormone (iPTH) level was found to be >600 pg/mL in cyst aspiration fluid. Left lobectomy was performed, with a diagnosis of primary hyperparathyroidism due to functional parathyroid cyst. Serum iPTH level was decreased >50% postoperatively and histopathological evaluation was consistent with an encapsulated parathyroid adenoma with a cystic center. Parathyroid cysts are among rare causes of primary hyperparathyroidism. Diagnosis is made by markedly increased iPTH level in cyst fluid and observation of parathyroid epithelium lining the cyst wall. |
| Databáze: | OpenAIRE |
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