Thermally Driven Approach To Fill Sub-10-nm Pipettes with Batch Production
| Autor: | Linhao Sun, Shinji Watanabe, Toshio Ando, Kazuki Shigyou |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Nanostructure
business.industry Chemistry 010401 analytical chemistry Pipette FOS: Physical sciences Conductance Applied Physics (physics.app-ph) Physics - Applied Physics Radius Condensed Matter - Soft Condensed Matter 010402 general chemistry 01 natural sciences Electrical contacts 0104 chemical sciences Analytical Chemistry Characterization (materials science) Temperature gradient Transmission electron microscopy Soft Condensed Matter (cond-mat.soft) Optoelectronics business |
| Zdroj: | Analytical Chemistry. 91:14080-14084 |
| ISSN: | 1520-6882 0003-2700 |
| DOI: | 10.1021/acs.analchem.9b03848 |
| Popis: | Typically, utilization of small nanopipettes results in either high sensitivity or spatial resolution in modern nanoscience and nanotechnology. However, filling a nanopipette with a sub-10-nm pore diameter remains a significant challenge. Here, we introduce a thermally driven approach to filling sub-10-nm pipettes with batch production, regardless of their shape. A temperature gradient is applied to transport water vapor from the backside of nanopipettes to the tip region until bubbles are completely removed from this region. The electrical contact and pore size for filling nanopipettes are confirmed by current-voltage and transmission electron microscopy (TEM) measurements, respectively. In addition, we quantitatively compare the pore size between the TEM characterization and estimation on the basis of pore radius and conductance. The validity of this method provides a foundation for highly sensitive detection of single molecules and high spatial resolution imaging of nanostructures. 7 pages, 4 figures |
| Databáze: | OpenAIRE |
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