Hypertriglyceridemia, an important and independent risk factor for acute pancreatitis in patients with type 2 diabetes mellitus
| Autor: | Mirela Frandes, Oana Albai, Deiana Roman |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
acute pancreatitis hypertriglyceridemia Gastroenterology 03 medical and health sciences 0302 clinical medicine Insulin resistance Diabetes mellitus Internal medicine insulin resistance medicine Pharmacology (medical) General Pharmacology Toxicology and Pharmaceutics Risk factor Glycemic Original Research Chemical Health and Safety business.industry Hypertriglyceridemia Type 2 Diabetes Mellitus General Medicine medicine.disease 030220 oncology & carcinogenesis diabetes mellitus Acute pancreatitis Pancreatitis 030211 gastroenterology & hepatology business Safety Research |
| Zdroj: | Therapeutics and Clinical Risk Management |
| ISSN: | 1176-6336 |
| Popis: | PURPOSE Acute pancreatitis (AP) is a frequent inflammatory disease of the pancreas with multiple causes, among which high triglyceride (TG) level is the most common. The main purpose of this study has been to research the prevalence of AP in patients with diabetes mellitus (DM) and to underline the importance of hypertriglyceridemia (HTG) as a risk factor in triggering AP. The possible link between AP and glycemic control has been studied also, alongside some cardiovascular risk factors and long-term diabetes complications. PATIENTS AND METHODS The patient cohort comprised 1,586 patients with DM, admitted to the Internal Medicine Clinic of Diabetes, Nutrition and Metabolic Disease within the Emergency Hospital in Timisoara between January and August 2016. Following a series of clinical and biological investigations, these patients were diagnosed with AP. The patients' antidiabetic treatment and chronic diabetes-related complications have also been recorded. RESULTS The prevalence of pancreatitis in this group of patients was 3.7%. The presence of pancreatitis was associated with a higher HbA1c (8.5% vs 7.7%; P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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