Efficacy of anti-diarrheal activity of Pedalium murex L., in wistar albino rats

Autor: V. Nithya, Anusha Baskar, R Haripriya, R Ravikumar, V Parkavi
Jazyk: angličtina
Předmět:
Zdroj: BMC Infectious Diseases
BMC Infectious Diseases, Vol 12, Iss Suppl 1, p P90 (2012)
ISSN: 1471-2334
DOI: 10.1186/1471-2334-12-s1-p90
Popis: Methods The ethyl acetate extract of Pedalium murex L., (250, 500, and 1000 mg/kg body weight) was administered orally to three groups of rats (five animals per group) in order to evaluate the activity of the extract against castor oil-induced diarrhea model in rat. Two other groups received normal saline (5mg/kg) and loperamide (5mg/kg) as positive control. The effect of the extract on intestinal transit and castor oil-induced intestinal fluid accumulation (enteropooling) was assessed.
Databáze: OpenAIRE