Efficacy of anti-diarrheal activity of Pedalium murex L., in wistar albino rats
Autor: | V. Nithya, Anusha Baskar, R Haripriya, R Ravikumar, V Parkavi |
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Jazyk: | angličtina |
Předmět: |
Loperamide
Veterinary medicine Traditional medicine business.industry medicine.medical_treatment Ethyl acetate Positive control Intestinal fluid lcsh:Infectious and parasitic diseases Pedalium murex chemistry.chemical_compound Diarrhea Infectious Diseases chemistry Poster Presentation Medicine lcsh:RC109-216 medicine.symptom business Saline Anti-Diarrheal medicine.drug |
Zdroj: | BMC Infectious Diseases BMC Infectious Diseases, Vol 12, Iss Suppl 1, p P90 (2012) |
ISSN: | 1471-2334 |
DOI: | 10.1186/1471-2334-12-s1-p90 |
Popis: | Methods The ethyl acetate extract of Pedalium murex L., (250, 500, and 1000 mg/kg body weight) was administered orally to three groups of rats (five animals per group) in order to evaluate the activity of the extract against castor oil-induced diarrhea model in rat. Two other groups received normal saline (5mg/kg) and loperamide (5mg/kg) as positive control. The effect of the extract on intestinal transit and castor oil-induced intestinal fluid accumulation (enteropooling) was assessed. |
Databáze: | OpenAIRE |
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