Predictors of left ventricular ejection function decline in young patients with ST-segment elevation myocardial infarction

Autor: Ibrahim Yildiz, Ibrahim Rencüzoğulları, Yavuz Karabağ, Muammer Karakayali, Inanc Artac, Mehmet Sait Gurevin
Rok vydání: 2022
Předmět:
Zdroj: Revista da Associação Médica Brasileira, Volume: 68, Issue: 6, Pages: 802-807, Published: 24 JUN 2022
Revista da Associação Médica Brasileira v.68 n.6 2022
Revista da Associação Médica Brasileira
Associação Médica Brasileira (AMB)
instacron:AMB
ISSN: 1806-9282
0104-4230
Popis: SUMMARY OBJECTIVE: A decrease in the left ventricular ejection fraction (≤40%) in the setting of ST-segment elevation myocardial infarction is a significant predictor of mortality in the young ST-segment elevation myocardial infarction population. In this study, we aimed to investigate the predictors of left ventricular ejection fraction reduction and evaluate the long-term mortality rates in young ST-segment elevation myocardial infarction patients with or without decreased left ventricular ejection fraction. METHODS: We enrolled retrospectively 411 consecutive ST-segment elevation myocardial infarction patients aged 45 years or below who underwent primary percutaneous coronary intervention. Young ST-segment elevation myocardial infarction patients were divided into two groups according to their left ventricular ejection fraction (≤40%, n=72 and >40%, n=339), which were compared with each other. RESULTS: Statin use, white blood cell count, C-reactive protein, peak creatine kinase-MB, prolonged ischemia time, left anterior descending artery-related infarction, proximally/ostial located lesion, and no-reflow were independently associated with low left ventricular ejection fraction. Additionally, long-term mortality was considerably higher in the left ventricular ejection fraction ≤40% group than those in the left ventricular ejection fraction>40% group (18.1% versus 2.4%; p
Databáze: OpenAIRE
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