IPCS harmonization of methods for the prediction and quantification of human carcinogenic/mutagenic hazard, and for indicating the probable mechanism of action of carcinogens
| Autor: | C. Sonich-Mullin, J. Preston, R. Fielder, George C. Becking, George R. Douglas, J. Ashby, M.D. Shelby, H.N.B. Gopalan, Michael D. Waters, Ilse-Dore Adler, Diana Anderson, T. Sofuni |
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| Rok vydání: | 1996 |
| Předmět: |
business.industry
Mutagenicity Tests Health Toxicology and Mutagenesis Harmonization Rodentia Hazard Risk Assessment Toxicology Chemical safety Germ Cells Flow chart Environmental health Genetics Carcinogens Medicine Animals Humans business Mutagenicity Test Risk assessment Molecular Biology Carcinogen Probable mechanism Mutagens |
| Zdroj: | Mutation research. 352(1-2) |
| ISSN: | 0027-5107 |
| Popis: | A flow chart is presented as a recommended sequence of tests to predict the carcinogenic hazard, and to predict and quantify the mutagenic hazard to germ cells of chemicals to humans. Ten associated principles of testing for these endpoints are also suggested. These recommendations are the result of a meeting convened under the auspices of the International Programme on Chemical Safety (IPCS), as part of their project on 'Harmonization of Approaches to the Assessment of Risk from Exposure to Chemicals'. The meeting was held at Carshalton, Surrey, from 13-17 February 1995. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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