Characterization of friction and moisture of porcine lingual tissue in vitro in response to artificial saliva and mouthwash solutions

Autor:	H. M. Trivedi, J. G. Masters, J. Zundel, Shamim Ansari, Stephen A. Mascaro
Rok vydání:	2018
Předmět:	Friction coefficient Saliva Materials science integumentary system Moisture Friction Swine Mouthwashes Saliva Artificial 04 agricultural and veterinary sciences Dermatology Tribology In Vitro Techniques 040401 food science Frictional coefficient body regions 0404 agricultural biotechnology stomatognathic system Tongue Animals Coefficient of friction human activities Water content Biomedical engineering
Zdroj:	Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI). 24(4)
ISSN:	1600-0846
Popis:	BACKGROUND The purpose of this research is to characterize the effects of mouthwash solutions on oral friction and moisture using a quantitative in vitro approach. MATERIALS AND METHODS The frictional coefficient of in vitro porcine tongue samples was measured using a magnetic levitation haptic device equipped with a custom tactor designed to mimic human skin. A commercially available moisture meter was used to measure moisture content of the samples. Tongue samples were first tested before treatment, then after application of saliva (either human or artificial), and again after application of 1 of 11 different mouthwash solutions. RESULTS The data indicate that the samples treated with artificial saliva vs real saliva have comparable friction coefficient and moisture content. Furthermore, the moisture and friction coefficient remain relatively constant for up to 60 minutes after exposure to ambient conditions. Samples treated with artificial saliva have an average friction coefficient in the range of 0.70-0.80. Application of mouthwash solutions produced an average friction coefficient of 0.39-0.49 but retained the high moisture content of the artificial salivary layer. Several mouthwash solutions resulted in statistically significant differences in the friction coefficient relative to each other. CONCLUSION The results of this study demonstrate that a magnetic levitation device can be an effective tool for in vitro oral tribology and that artificial saliva is an effective substitute for real saliva in extended in vitro experiments. The application of mouthwash generally reduces the coefficient of friction of the tongue samples while preserving a relatively high moisture level, and some mouthwashes reduce friction significantly more than others.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f58aafe1dde7aed247754004bb2a1799 https://pubmed.ncbi.nlm.nih.gov/29736996 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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