Detection of Local Recurrence After Radical Prostatectomy by Prostate Specific Antigen and Transrectal Ultrasound
| Autor: | Avi Stein, Jean B. deKernion, Michael T. Macfarlane, Antoine S. Abi-Aad |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Male
medicine.medical_specialty Biopsy Urology medicine.medical_treatment Rectum Antigens Neoplasm Prostate Biomarkers Tumor medicine Recurrent disease Humans Postoperative Period Ultrasonography Prostatectomy medicine.diagnostic_test business.industry Ultrasound Prostatic Neoplasms Rectal examination Prostate-Specific Antigen Surgery Prostate-specific antigen medicine.anatomical_structure Radiology Neoplasm Recurrence Local business |
| Zdroj: | Journal of Urology. 147:952-955 |
| ISSN: | 1527-3792 0022-5347 |
| DOI: | 10.1016/s0022-5347(17)37431-1 |
| Popis: | Twenty patients with detectable levels of prostate specific antigen (PSA) after radical prostatectomy with no identifiable distant metastases were evaluated for local recurrence by digital rectal examination and transrectal ultrasound combined with biopsies. Of the patients 9 (45%) were found to have histological evidence of local recurrence at the initial assessment. All 4 patients with an abnormal digital rectal examination had recurrent disease. Transrectal ultrasound displayed abnormalities in 12 of the 20 patients, 7 of whom had positive biopsies. Random biopsies of the vesicourethral junction were performed in 8 patients who had negative ultrasound findings and an unremarkable digital rectal examination, of whom 2 had histological documentation of local recurrence. Complications occurred in 1 patient (5%) who presented with clot retention. We conclude that PSA is an excellent tool for identification of recurrent disease after radical prostatectomy, and transrectal ultrasound guided biopsy is a useful diagnostic approach in patients suspected of local failure, especially when the digital rectal examination is unremarkable. |
| Databáze: | OpenAIRE |
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