Association of different oral anticoagulants use with renal function worsening in patients with atrial fibrillation: A multicentre cohort study

Autor:	Martina Berteotti, Marco Antonio Casciaro, Daniele Pastori, Gregory Y.H. Lip, Francesco Violi, Vito Menafra, Evaristo Ettorre, Mirella Saliola, Cosmo Godino, Francesco Melillo, Francesco Perticone, Pasquale Pignatelli, Rossella Marcucci, Danilo Menichelli, Angela Sciacqua
Rok vydání:	2020
Předmět:	Male renal failure medicine.medical_specialty Administration Oral Angiotensin-Converting Enzyme Inhibitors direct oral anticoagulants 030226 pharmacology & pharmacy Gastroenterology Dabigatran Cohort Studies Angiotensin Receptor Antagonists 03 medical and health sciences 0302 clinical medicine Rivaroxaban Interquartile range Internal medicine Atrial Fibrillation medicine anticoagulation treatment Humans Pharmacology (medical) Prospective Studies 030212 general & internal medicine Prospective cohort study Aged Aged 80 and over Pharmacology business.industry Warfarin Anticoagulants Atrial fibrillation Original Articles Odds ratio Middle Aged medicine.disease warfarin Stroke Female Kidney Diseases Apixaban atrial fibrillation business medicine.drug
Zdroj:	Br J Clin Pharmacol
ISSN:	1365-2125 0306-5251
DOI:	10.1111/bcp.14350
Popis:	AIMS: To investigate the decline of estimated glomerular filtration rate (eGFR) in patients with atrial fibrillation (AF) treated with vitamin K antagonists (VKAs) or non‐VKA oral anticoagulants (NOACs). METHODS: Multicentre prospective cohort study including 1667 patients with nonvalvular AF. The eGFR was assessed by the CKD‐EPI formula at baseline and during follow‐up. The primary endpoint of the study was the median annual decline of eGFR according to VKA (n = 743) or NOAC (n = 924) use. As secondary endpoints, we analysed the transition to eGFR
Databáze:	OpenAIRE
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