The association of infectious mononucleosis and invasive breast cancer in The Health of Women (HOW) Study

Autor:	Yujing Jan Heng, Susan Love, Jessica Clague DeHart, Joyce D. Fingeroth, Gerburg M. Wulf
Rok vydání:	2021
Předmět:	Adult Epstein-Barr Virus Infections Herpesvirus 4 Human Adolescent Breast Neoplasms General Medicine Young Adult Logistic Models Oncology Humans Pharmacology (medical) Radiology Nuclear Medicine and imaging Female Infectious Mononucleosis Child
Zdroj:	Breast cancer (Tokyo, Japan). 29(4)
ISSN:	1880-4233
Popis:	The link between Epstein-Barr Virus (EBV) and breast cancer (BC) etiology remains unclear. We utilized the Health of Women (HOW) StudyThe HOW StudyA history of IM was associated with a lower likelihood of developing invasive BC compared to women who did not develop IM (adjusted OR = 0.83, 95% CI 0.72-0.94). That finding was driven by women who had IM between 10 and 22 years old (adjusted OR = 0.83, 95% CI 0.72-0.97) albeit no linear association between age at developing IM and breast cancer (p-trend 0.05). Women who had IM between 10 and 22 years old were less likely to develop estrogen receptor positive (ER+ ; adjusted OR = 0.84, 95% CI 0.71-0.99) or hormone receptor positive (HR+ ; adjusted OR = 0.86, 95% CI 0.73-1.01) BC. There was no association between IM and ER- or HR- BC.In the HOW Study
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f586a44d0c2cf39d797b2102339cdcde https://pubmed.ncbi.nlm.nih.gov/35347575 Zobrazit plný text záznamu Full text from SpringerLink