Jammed Microgel Inks for 3D Printing Applications
| Autor: | Christopher B. Highley, Kwang Hoon Song, Andrew C. Daly, Jason A. Burdick |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Materials science
General Chemical Engineering Mixing (process engineering) General Physics and Astronomy Medicine (miscellaneous) 3D printing Nanotechnology 02 engineering and technology 010402 general chemistry 01 natural sciences Biochemistry Genetics and Molecular Biology (miscellaneous) microgels chemistry.chemical_compound Rheology inks Deposition (phase transition) General Materials Science hydrogels Inkwell business.industry Communication General Engineering 021001 nanoscience & nanotechnology Communications 0104 chemical sciences chemistry Self-healing hydrogels Particle 0210 nano-technology business Ethylene glycol biomaterials |
| Zdroj: | Advanced Science |
| ISSN: | 2198-3844 |
| Popis: | 3D printing involves the development of inks that exhibit the requisite properties for both printing and the intended application. In bioprinting, these inks are often hydrogels with controlled rheological properties that can be stabilized after deposition. Here, an alternate approach is developed where the ink is composed exclusively of jammed microgels, which are designed to incorporate a range of properties through microgel design (e.g., composition, size) and through the mixing of microgels. The jammed microgel inks are shear‐thinning to permit flow and rapidly recover upon deposition, including on surfaces or when deposited in 3D within hydrogel supports, and can be further stabilized with secondary cross‐linking. This platform allows the use of microgels engineered from various materials (e.g., thiol‐ene cross‐linked hyaluronic acid (HA), photo‐cross‐linked poly(ethylene glycol), thermo‐sensitive agarose) and that incorporate cells, where the jamming process and printing do not decrease cell viability. The versatility of this particle‐based approach opens up numerous potential biomedical applications through the printing of a more diverse set of inks. |
| Databáze: | OpenAIRE |
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