Screening for Human Parvovirus B19 Infection in Egyptian Family Replacement Blood Donors
Autor: | Hanaa H.A. Gomaa, Fadia M. Attia, Rabab Hasanain Ahmed Hasanain, Rania M. Saleh |
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Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
medicine.medical_specialty
Blood transfusion medicine.medical_treatment viruses Human parvovirus 030204 cardiovascular system & hematology Serology 03 medical and health sciences 0302 clinical medicine Internal medicine hemic and lymphatic diseases medicine Suez canal Hematology biology business.industry virus diseases University hospital Serum samples Virology biology.protein Original Article Antibody business 030215 immunology |
Zdroj: | Indian J Hematol Blood Transfus |
Popis: | Up till now, screening for human parvovirus B19 is not routine in national Egyptian blood bank strategy. Blood samples were collected from 500 healthy blood donors within the age range from 18 to 45 years old attending the blood bank of Suez Canal University Hospital, Ismailia, Egypt. Sera were separated and stored at − 20 °C. Serum samples were screened for anti-human parvovirus B19 IgM and IgG antibodies and B19 genome using ELISA and real-time PCR respectively. Frequency of B19 IgM and B19 IgG antibodies was 6.20%, and 80.20% respectively, and the prevalence of B19 genome was 3.00%. There is a high frequency of human parvovirus B19 among Egyptian blood donors; therefore, serological screening for B19 is warranted. |
Databáze: | OpenAIRE |
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