The presence of large amounts of type III collagen in bovine dental pulp and its significance with regard to the mechanism of dentinogenesis
| Autor: | J.H. Lechner, G. Kalnitsky |
|---|---|
| Rok vydání: | 1981 |
| Předmět: |
Molar
Dentistry Hydroxylation chemistry.chemical_compound stomatognathic system Animals Cyanogen Bromide Amino Acids General Dentistry Polyacrylamide gel electrophoresis Dental Pulp Chemistry business.industry Cell Biology General Medicine Dentinogenesis Pepsin A stomatognathic diseases Electrophoresis Otorhinolaryngology Biochemistry Molar mass distribution Pulp (tooth) Cattle Electrophoresis Polyacrylamide Gel Cyanogen bromide Collagen business |
| Zdroj: | Archives of Oral Biology. 26:265-273 |
| ISSN: | 0003-9969 |
| DOI: | 10.1016/0003-9969(81)90046-7 |
| Popis: | Type I and type III collagens were isolated from the pulp of bovine molar teeth. The molecular species α1(I), α2, and α1(III) were identified by Chromatographic behaviour, electrophoretic mobility, amino acid composition and molecular weight distribution of CNBr cleavage products. The proportions of type I and type III collagen were determined by quantitative electrophoresis of CNBr digests of whole tissue. Pulp specimens were selected to represent stages of active, moderate and inactive dentinogenesis. The total collagen content of pulp increased with maturity, but type III was constant 45 per cent of the total collagen at each stage. Thus, the collagen of dental pulp is chemically distinct from that of dentine. These findings indicate that dental pulp collagen cannot be the immediate precursor of dentine collagen. |
| Databáze: | OpenAIRE |
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