Sinonasal undifferentiated carcinoma: Report of a case and review of literature
Autor: | Adam V. Jones, Paul M. Speight, Ivan Robinson |
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Rok vydání: | 2005 |
Předmět: |
Nasal cavity
Undifferentiated carcinoma Pathology medicine.medical_specialty business.industry Carcinoma Nasal sinuses Nose medicine.disease Glandular Differentiation Pathology and Forensic Medicine Sinonasal undifferentiated carcinoma Paranasal sinuses medicine.anatomical_structure Pleomorphism (cytology) Oncology Otorhinolaryngology EBV Nasopharynx medicine Differential diagnosis Oral Surgery business |
Zdroj: | Oral Oncology Extra. 41(10):299-302 |
ISSN: | 1741-9409 |
DOI: | 10.1016/j.ooe.2005.07.007 |
Popis: | Summary Sinonasal undifferentiated carcinomas (SNUC) are highly aggressive lesions arising in the superior nasal cavity and paranasal sinuses. The differential diagnosis may be wide since a range of similar lesions may present at this site. Recently the criteria for diagnosis of SNUC has been clarified. Histologically they show marked pleomorphism, mitotic activity and necrosis with no evidence of squamous or glandular differentiation or of rosettes. They express low molecular weight cytokeratins and are typically negative for S-100 and neuroendocrine markers. They do not express EBV. |
Databáze: | OpenAIRE |
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