Comparison of vascular responses after different types of second-generation drug-eluting stents implantation detected by optical coherence tomography
| Autor: | Kazuto Hayasaka, Keisuke Kojima, Mitsuaki Isobe, Takashi Ashikaga, Shigeki Kimura, Keiichi Hishikari, Yuichiro Sagawa, Tomoyo Sugiyama, Hirofumi Ohtani, Toru Misawa, Hiroyuki Hikita, Masafumi Mizusawa, Atsushi Takahashi, Yosuke Yamakami |
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| Rok vydání: | 2016 |
| Předmět: |
Male
Neointima medicine.medical_specialty Time Factors medicine.medical_treatment Coronary Artery Disease 030204 cardiovascular system & hematology Prosthesis Design 03 medical and health sciences Percutaneous Coronary Intervention 0302 clinical medicine Restenosis Optical coherence tomography Predictive Value of Tests medicine Humans Radiology Nuclear Medicine and imaging Everolimus 030212 general & internal medicine Stent thrombosis Aged Retrospective Studies Sirolimus Neointimal hyperplasia medicine.diagnostic_test business.industry Stent Cardiovascular Agents Drug-Eluting Stents Middle Aged medicine.disease Coronary Vessels Apposition Treatment Outcome Metals Homogeneous Female Radiology Cardiology and Cardiovascular Medicine Nuclear medicine business Tomography Optical Coherence |
| Zdroj: | The International Journal of Cardiovascular Imaging. 33:177-186 |
| ISSN: | 1573-0743 1569-5794 |
| Popis: | Few studies have directly compared vascular responses to second-generation drug-eluting stents (DESs). We performed optical coherence tomography examinations in 56 consecutive patients with implanted single stent [19 cobalt-chromium everolimus-eluting stents (CoCr-EES), 22 platinum-chromium EES (PtCr-EES), and 15 resolute zotarolimus-eluting stents (R-ZES)] for de novo lesions, and who did not have restenosis at their 9-month follow-up. Neointimal thickness (NIT), stent apposition, and neointimal coverage were assessed in every strut. A neointimal unevenness score [(NUS), maximum NIT/average NIT in the same cross-section] was determined for every 1-mm cross-section (CS). A total of 8350 struts and 1159 CSs were analyzed. The CoCr- and PtCr-EES had significantly fewer malapposed struts compared to the R-ZES (CoCr-EES: 0.19 % vs. PtCr-EES: 0.19 % vs. R-ZES: 0.61 %, p = 0.007). Furthermore, the PtCr-EES had a lower frequency of uncovered struts compared to the others (CoCr-EES: 2.0 % vs. PtCr-EES: 1.4 % vs. R-ZES: 2.3 %, p = 0.047). The NUS correlated with the frequency of uncovered struts (p |
| Databáze: | OpenAIRE |
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