Acridinium Ester Chemiluminescence: Methyl Substitution on the Acridine Moiety
| Autor: | Kenji Hamase, Takeyuki Akita, Manabu Nakazono, Shinkoh Nanbu |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
chemistry.chemical_classification
Luminescence Trifluoromethyl General Chemical Engineering Salt (chemistry) Electrons Esters Hydrogen Peroxide General Medicine General Chemistry Hydrogen-Ion Concentration Medicinal chemistry law.invention chemistry.chemical_compound chemistry law Acridine Nitro Acridines Moiety Hydrogen peroxide Trifluoromethanesulfonate Chemiluminescence |
| Zdroj: | Journal of Oleo Science. 70:1677-1684 |
| ISSN: | 1347-3352 1345-8957 |
| Popis: | Methyl groups were introduced on the acridine moiety in chemiluminescent acridinium esters that have electron-withdrawing groups (trifluoromethyl, cyano, nitro, ethoxycarbonyl) at the 4-position on the phenyl ester. The introduction of methyl groups at the 2-, 2,7-, and 2,3,6,7-positions on the acridine moiety shifted the optimal pH that gave relatively strong chemiluminescence intensity from neutral conditions to alkaline conditions. 4-(Ethoxycarbonyl)phenyl 2,3,6,7,10-pentamethyl-10λ4-acridine-9-carboxylate, trifluoromethanesulfonate salt showed long-lasting chemiluminescence under alkaline conditions. Acridinium esters to determine hydrogen peroxide concentration at pH 7-10 were newly developed. |
| Databáze: | OpenAIRE |
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