Proliferative and nonproliferative lesions of the rat and mouse respiratory tract
| Autor: | Thomas Wöhrmann, Birgit Kittel, Ron Herbert, Roger A. Renne, Michael V. Pino, Martin Rosenbruch, Jack R. Harkema, Kasuke Nagano, Amy E. Brix, Pierre Tellier, Susanne Rittinghausen, David B. Lewis, Thomas H. March |
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| Přispěvatelé: | Publica |
| Rok vydání: | 2009 |
| Předmět: |
Pathology
medicine.medical_specialty Internationality Tobacco-specific nitrosamine 040301 veterinary sciences beta-oxidized dipropylnitrosamine Cytokeratin expression patterns Respiratory System Respiratory Tract Diseases sprague-dawley rats Fischer 344 rat Toxicology 030226 pharmacology & pharmacy Pathology and Forensic Medicine 0403 veterinary science Lesion Rodent Diseases 03 medical and health sciences Mice 0302 clinical medicine Animals Laboratory Terminology as Topic Toxicity Tests long-term inhalation medicine Animals Titanium-dioxide particles International harmonization nasal cavity tumor Molecular Biology Inhalation Exposure business.industry gene-related peptide International Agencies 04 agricultural and veterinary sciences Cell Biology Respiratory Tract Neoplasms Rats medicine.anatomical_structure clara cell adenomas Histopathology medicine.symptom business Respiratory tract |
| Zdroj: | Toxicologic pathology. 37 |
| ISSN: | 1533-1601 |
| Popis: | The INHAND Project (International Harmonization of Nomenclature and Diagnostic Criteria for Lesions in Rats and Mice) is a joint initiative of the Societies of Toxicologic Pathology from Europe (ESTP), Great Britain (BSTP), Japan (JSTP) and North America (STP) to develop an internationally-accepted nomenclature for proliferative and non-proliferative lesions in laboratory animals. The purpose of this publication is to provide a standardized nomenclature for classifying microscopic lesions observed in the respiratory tract of laboratory rats and mice, with color photomicrographs illustrating examples of some lesions. The standardized nomenclature presented in this document is also available electronically on the inter-net (http://www.goreni.org/). Sources of material included histopathology databases from government, academia, and industrial laboratories throughout the world. Content includes spontaneous developmental and aging lesions as well as lesions induced by exposure to test materials. A widely accepted and utilized international harmonization of nomenclature for respiratory tract lesions in laboratory animals will decrease confusion among regulatory and scientific research organizations in different countries and provide a common language to increase and enrich international exchanges of information among toxicologists and pathologists. |
| Databáze: | OpenAIRE |
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