Orthostatic hypotension is associated with decreased cerebrospinal fluid levels of chromogranin A in early stage of Parkinson disease
| Autor: | Hana Prikrylova Vranova, Michaela Kaiserová, Jan Galuszka, David Stejskal, Petr Kanovsky, Jana Zapletalová, Katerina Mensikova, Jan Mares |
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| Rok vydání: | 2015 |
| Předmět: |
Male
endocrine system medicine.medical_specialty Parkinson's disease Neurology Hypotension Orthostatic Tilt table test Orthostatic vital signs Cerebrospinal fluid Tilt-Table Test Diabetes mellitus Internal medicine medicine Humans biology medicine.diagnostic_test Endocrine and Autonomic Systems business.industry Chromogranin A Parkinson Disease Middle Aged medicine.disease Endocrinology Blood pressure biology.protein Female sense organs Neurology (clinical) business Biomarkers |
| Zdroj: | Clinical Autonomic Research. 25:339-342 |
| ISSN: | 1619-1560 0959-9851 |
| Popis: | An association between the CSF chromogranin A (CgA) and orthostatic blood pressure changes was investigated in 20 patients in the early stage of Parkinson disease (PD). There was a positive correlation between the CSF CgA and diastolic blood pressure change, when CSF CgA levels were lower in patients with orthostatic hypotension (OH). Decreased CSF CgA may be useful in predicting OH in the early stage of PD. |
| Databáze: | OpenAIRE |
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