Cutaneous Pyogranulomas Associated with Nocardia jiangxiensis in a Cat from the Eastern Caribbean
| Autor: | Adam Silkworth, Ryan P. Cavanaugh, Pompei Bolfa, Anne A. M. J. Becker |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Microbiological culture 040301 veterinary sciences medicine.drug_class 030106 microbiology Antibiotics lcsh:Medicine Case Report actinomycetoma 0403 veterinary science one health 03 medical and health sciences skin and subcutis medicine feline nocardiosis General Immunology and Microbiology biology business.industry Sulfamethoxazole lcsh:R Nocardiosis Public Health Environmental and Occupational Health Nocardia 04 agricultural and veterinary sciences medicine.disease biology.organism_classification Trimethoprim Dermatology Infectious Diseases Cellulitis caribbean Panniculitis business medicine.drug |
| Zdroj: | Tropical Medicine and Infectious Disease, Vol 4, Iss 4, p 130 (2019) Tropical Medicine and Infectious Disease |
| ISSN: | 2414-6366 |
| Popis: | Nocardia spp. are worldwide, ubiquitous zoonotic bacteria that have the ability to infect humans as well as domestic animals. Herein, we present a case of a five-year-old female spayed domestic shorthair cat (from the island of Nevis) with a history of a traumatic skin wound on the ventral abdomen approximately two years prior to presenting to the Ross University Veterinary Clinic. The cat presented with severe dermatitis and cellulitis on the ventral caudal abdomen, with multiple draining tracts and sinuses exuding purulent material. Initial bacterial culture yielded Corynebacterum spp. The patient was treated symptomatically with antibiotics for 8 weeks. The cat re-presented 8 weeks after the initial visit with worsening of the abdominal lesions. Surgical intervention occurred at that time, and histopathology and tissue cultures confirmed the presence of Nocardia spp.-induced pyogranulomatous panniculitis, dermatitis, and cellulitis. Pre-operatively, the patient was found to be feline immunodeficiency virus (FIV)-positive. The patient was administered trimethoprim/sulfamethoxazole (TMS) after antimicrobial sensitivity testing. PCR amplification and 16S rRNA gene sequencing confirmed Nocardia jiangxiensis as the causative agent. To our knowledge, N. jiangxiensis has not been previously associated with disease. This case report aims to highlight the importance of a much-needed One Health approach using advancements in technology to better understand the zoonotic potential of Nocardia spp. worldwide. |
| Databáze: | OpenAIRE |
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