Spindle cell carcinoma of the mandible: Clinicopathological and immunohistochemical characteristics
| Autor: | Ramaa Balkaran, H.F. Al-Bayaty |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Pathology
medicine.medical_specialty Case Report Vimentin Biology medicine.disease Debulking stomatognathic diseases 03 medical and health sciences Cytokeratin 0302 clinical medicine medicine.anatomical_structure Otorhinolaryngology 030220 oncology & carcinogenesis Oral and maxillofacial pathology medicine biology.protein Carcinoma Immunohistochemistry Oral mucosa General Dentistry Spindle cell carcinoma |
| Zdroj: | Journal of Oral Biology and Craniofacial Research. 6:160-163 |
| ISSN: | 2212-4268 |
| DOI: | 10.1016/j.jobcr.2015.08.009 |
| Popis: | Spindle cell carcinoma, a rare variant of squamous cell carcinoma, has propensity to occur in the upper aero digestive tract, including the oral mucosa. In this oral pathology communication, we report the occurrence of this neoplasm in the left mandible as a large fleshy growth with destruction of bone in a 73-year-old Afro-Trinidadian female. The distinction of this tumor from other malignant spindle cell mesenchymal tumors is important. Selective sampling of this specimen for possible transitional areas of squamous and spindle cell appearance, immunohistochemical staining for cytokeratin, vimentin, and S-100 protein are helpful in establishing the diagnosis. According to the patient's insistence, debulking of the tumor was performed under general anesthesia. Eight months later the patient succumbed to the disease. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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