Antipsychotic-Induced Hyponatraemia

Autor: Meulendijks, L.A., Mannesse, C.K., Jansen, P.A.F., van Marum, R.J., Egberts, A.C.G., Pharmacoepidemiology, Population-based studies of drug treatment: from molecule to patient outcomes, Dep Farmaceutische wetenschappen
Rok vydání: 2010
Předmět:
Zdroj: Drug Safety, 33(2), 101. Springer International Publishing Switzerland
ISSN: 0114-5916
DOI: 10.2165/11319070-000000000-00000
Popis: Hyponatraemia is known to occur as a rare but clinically important adverse reaction to treatment with different psychotropic drugs, including selective serotonin reuptake inhibitors and antiepileptic drugs. In past decades, reports have been published that describe the development of hyponatraemia in association with antipsychotic drug treatment. Our objective was to systematically review the available evidence on antipsychotic-induced hyponatraemia, focussing on patient characteristics, drug dosage, polydipsia and the syndrome of inappropriate secretion of antidiuretic hormone (SIADH). A search was carried out in the MEDLINE and EMBASE databases from January 1966 to 11 April 2009. Inclusion criteria were (i) hyponatraemia (serum sodium level
Databáze: OpenAIRE