The benefits of magnetic resonance imaging methods to extend the knowledge of the anatomical organisation of the periaqueductal gray in mammals
| Autor: | Dóra Zelena, Elodie Chaillou, Frédéric Andersson, Ophélie Menant |
|---|---|
| Přispěvatelé: | Physiologie de la reproduction et des comportements [Nouzilly] (PRC), Centre National de la Recherche Scientifique (CNRS)-Université de Tours-Institut Français du Cheval et de l'Equitation [Saumur]-Institut National de la Recherche Agronomique (INRA), Imagerie et cerveau, Université de Tours-Institut National de la Santé et de la Recherche Médicale (INSERM), Université Francois Rabelais [Tours], Institute of Experimental Medicine [Budapest] (KOKI), Hungarian Academy of Sciences (MTA), Programme Hubert Curien, Balaton ref. 25129TG, Institut National de la Recherche Agronomique (INRA)-Institut Français du Cheval et de l'Equitation [Saumur]-Université de Tours-Centre National de la Recherche Scientifique (CNRS), Imagerie et cerveau (iBrain - Inserm U1253 - UNIV Tours ), Institut National de la Recherche Agronomique (INRA)-Institut Français du Cheval et de l'Equitation [Saumur]-Université de Tours (UT)-Centre National de la Recherche Scientifique (CNRS), Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM) |
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
[SDV.OT]Life Sciences [q-bio]/Other [q-bio.OT] Brain chemistry neuroanatomy pag Biology Periaqueductal gray 03 medical and health sciences Cellular and Molecular Neuroscience 0302 clinical medicine Neurochemical medicine Animals Humans Periaqueductal Gray magnetic resonance imaging mammals Brain Chemistry Cell specific medicine.diagnostic_test image par résonnance magnétique Functional connectivity neuroanatomie mammifère Magnetic resonance imaging connections 030104 developmental biology medicine.anatomical_structure nervous system immunohistochemistry cerveau [SPI.SIGNAL]Engineering Sciences [physics]/Signal and Image processing Neuroscience 030217 neurology & neurosurgery nissl staining Neuroanatomy |
| Zdroj: | Journal of Chemical Neuroanatomy Journal of Chemical Neuroanatomy, Elsevier, 2016, 77, pp.110-120. ⟨10.1016/j.jchemneu.2016.06.003⟩ |
| ISSN: | 0891-0618 |
| DOI: | 10.1016/j.jchemneu.2016.06.003 |
| Popis: | The periaqueductal gray (PAG) is a mesencephalic brain structure involved in the expression of numerous behaviours such as maternal, sexual and emotional. Histological approaches showed the PAG is composed by subdivisions with specific cell organisation, neurochemical composition and connections with the rest of the brain. The comparison of studies performed in rodents and cats as the most often examined species, suggests that PAG organisation differs between mammals. However, we should also consider the plurality of the methods used in these studies that makes difficult the comparison of the PAG organisation between species. Therefore, to study the PAG in all mammals including human, the most relevant in vivo imaging method seems to be the magnetic resonance imaging (MRI). The purpose of this review was to summarize the knowledge of the anatomical organisation of the PAG in mammals and highlights the benefits of MRI methods to extend this knowledge. Results obtained by MRI so far support the conclusions of ex vivo studies, especially to describe the subdivisions and the connections of the PAG. In these latter, diffusion-weighted MRI and functional connectivity seem the most appropriate methods. In conclusion firstly, the MRI seems to be the best judicious method to compare species and improve the comprehension of the role of the PAG. Secondly, MRI is an in vivo method aimed to manage repeated measures in the same cohort of subjects allowing to study the impact of aging and the development on the anatomical organisation of the PAG. |
| Databáze: | OpenAIRE |
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