Ambient light induced antibacterial action of curcumin/graphene nanomesh hybrids
| Autor: | Zoran Marković, Vladimir B. Pavlović, N. K. Stanković, Danka Matijasevic, Miomir Nikšić, B. Todorović Marković, Ivanka Holclajtner-Antunović, Zdeno Spitalsky, Svetlana Jovanovic, Dušan Milivojević, Danica Bajuk-Bogdanović, Dejan P. Kepić |
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| Rok vydání: | 2017 |
| Předmět: |
Chemistry
Graphene General Chemical Engineering 02 engineering and technology General Chemistry 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences Exfoliation joint 0104 chemical sciences law.invention chemistry.chemical_compound Nanomesh Highly oriented pyrolytic graphite law Curcumin Organic chemistry Surface modification Ammonium persulfate 0210 nano-technology Antibacterial activity Nuclear chemistry |
| Zdroj: | RSC Advances |
| ISSN: | 2046-2069 |
| Popis: | Curcumin and its derivates are well-known for their different biological activities including antibacterial. On the other hand there are controversial reports concerning the antibacterial potential of graphene and, in particular, graphene oxide. In this study we have reported for the first time the antibacterial activity of curcumin/graphene nanomesh hybrids under ambient light conditions. The graphene nanomesh was synthesized by electrochemical exfoliation of highly oriented pyrolytic graphite in 1 M solution of ammonium persulfate and further functionalized by curcumin. Identical values of minimum inhibitory concentration (1 mg mL(-1)) were determined for pure curcumin and curcumin/graphene nanomesh hybrids toward Staphylococcus aureus. All tested samples had more pronounced antibacterial activity against Gram positive bacteria, Staphylococcus aureus compared to Escherichia coli as a representative of Gram negative strains. The poor antibacterial potential of exfoliated graphene improves significantly by the functionalization with curcumin, which allows for its usage as a antibacterial coating. |
| Databáze: | OpenAIRE |
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