| Autor: |
Zhanqian Yu, Marcin Ptaszek, Kannan Muthukumaran, Kelly A. Gauger, Melanie A. Ehudin, Masahiko Taniguchi, Vanampally Chandrashaker, Doyoung Ra, Daniel C. Talley, Thiagarajan Balasubramanian, Jonathan S. Lindsey |
| Rok vydání: |
2015 |
| Předmět: |
|
| Zdroj: |
Journal of porphyrins and phthalocyanines. 19(4) |
| ISSN: |
1088-4246 |
| Popis: |
Advances in chlorin synthetic chemistry now enable the de novo preparation of diverse chlorin-containing molecular architectures. Five distinct molecular designs have been explored here, including hydrophobic bioconjugatable (oxo)chlorins; a hydrophilic bioconjugatable chlorin; a trans-ethynyl/iodochlorin building block; a set of chlorins bearing electron-rich (methoxy, dimethylamino, methylthio) groups at the 3-position; and a set of ten 3,13-disubstituted chlorins chiefly bearing groups with extended π-moieties. Altogether 23 new chlorins (17 targets, 6 intermediates) have been prepared. The challenge associated with molecular designs that encompass the combination of "hydrophilic, bioconjugatable and wavelength-tunable" chiefly resides in the nature of the hydrophilic unit. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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