Damage Assessment of Spinal Bones Due to Prostate Cancer
Autor: | Octavio Andrés González-Estrada, Jabid Quiroga Méndez, Sergio Andrés Ardila Parra |
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Přispěvatelé: | González-Estrada, Octavio Andrés, Grupo de Investigación en Energía y Medioambiente [Bucaramanga]] (GIEMA), Universidad Industrial de Santander [Bucaramanga] (UIS) |
Jazyk: | angličtina |
Rok vydání: | 2018 |
Předmět: |
Computer science
spinal Lumbar vertebrae bone segmentation 030218 nuclear medicine & medical imaging Metastasis 03 medical and health sciences Prostate cancer 0302 clinical medicine Medical imaging medicine metastasis General Materials Science Segmentation FEA ComputingMilieux_MISCELLANEOUS Mechanical Engineering Stiffness medicine.disease bone damage Finite element method [SPI.MECA.STRU]Engineering Sciences [physics]/Mechanics [physics.med-ph]/Mechanics of the structures [physics.class-ph] Vertebra medicine.anatomical_structure Mechanics of Materials 030220 oncology & carcinogenesis [SPI.MECA.STRU] Engineering Sciences [physics]/Mechanics [physics.med-ph]/Structural mechanics [physics.class-ph] medicine.symptom Biomedical engineering |
Zdroj: | Key Engineering Materials Key Engineering Materials, Trans Tech Publications, 2018, 774, pp.149-154. ⟨10.4028/www.scientific.net/KEM.774.149⟩ 17th International Conference on Fracture and Damage Mechanics 17th International Conference on Fracture and Damage Mechanics, Sep 2018, Seville, Spain |
ISSN: | 1013-9826 1662-9795 |
DOI: | 10.4028/www.scientific.net/KEM.774.149⟩ |
Popis: | International audience; The present research proposes a methodology to determine the strength of a spinal bone in patients who suffer from prostate cancer using diagnostic imaging, with the purpose of verifying if metastasis has occurred, and critical conditions have been reached. Advanced numerical methods allow the modelling of anisotropic materials for different applications in biomedical engineering. The computed tomography images (CAT) provide the information to create a 3D model of the bone, in this case, the lumbar vertebra L5. Using segmentation software, it is possible to identify the mechanical properties of the materials that form the bone and define anisotropic conditions. The 3D anisotropic model is evaluated using finite element analysis (FEA), considering the appropriate boundary conditions and its respective material properties, and compared with the reference case of a healthy bone in an initial stage to assess the damage. Indicators based on the changes in stiffness of the vertebra could provide evidence of the need for chirurgical intervention. |
Databáze: | OpenAIRE |
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