Evidence of motor injury due to damaged corticospinal tract following acute hemorrhage in the basal ganglia region

Autor: Si Yuan Hou, Ling Shan Chen, Zhong Qiu Wang, Xue Hu Wei, Zheng Qiu Zhu, Xiao Kun Fang, Yong Kang Liu, Jing Li
Rok vydání: 2019
Předmět:
Zdroj: Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Scientific Reports
ISSN: 2045-2322
Popis: The integrity of the corticospinal tract (CST) is significantly affected following basal ganglia haemorrhage. We aimed to assess the local features of CST and to effectively predict motor function by diffusion characteristics of CST in patients with motor injury following acute haemorrhage in the acute basal ganglia region. We recruited 37 patients with paresis of the lateral limbs caused by acute basal ganglia haemorrhage. Based on the automated fiber quantification method to track CST, assessed the character of each CST segment between the affected and contralateral sides, and correlated these with the Fugl–Meyer (FM) and Barthel Index (BI) scores at 6 months after onset. The fractional anisotropy (FA) values of the injured side of CST showed a significantly lower FA than the contralateral side along the tract profiles (p
Databáze: OpenAIRE