Introduction of point-of-care testing in Japanese outpatient clinics is associated with improvement in time in therapeutic range in anticoagulant-treated patients
| Autor: | Hiroyuki Takai, Issei Komuro, Yoshihide Sakaguchi, Hiroshi Matsuo, Masaharu Masuda, Shinsuke Nanto, Yuji Okuyama, Toshio Amano, Seiji Adachi, Yasushi Sakata, Miyuki Matsuo, Masaki Togawa, Hitoshi Minamiguchi, Teruhiko Ryomoto, Yasunori Horiguchi |
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| Rok vydání: | 2014 |
| Předmět: |
Male
endocrine system medicine.medical_specialty Time Factors medicine.drug_class Point-of-care testing Point-of-Care Systems Time in therapeutic range Ambulatory Care Facilities Internal medicine medicine Outpatient clinic Humans cardiovascular diseases Stroke Aged Prothrombin time Aged 80 and over medicine.diagnostic_test business.industry Anticoagulant Warfarin nutritional and metabolic diseases Anticoagulants Atrial fibrillation General Medicine Middle Aged medicine.disease Emergency medicine Prothrombin Time Female Cardiology and Cardiovascular Medicine business medicine.drug |
| Zdroj: | Circulation journal : official journal of the Japanese Circulation Society. 78(6) |
| ISSN: | 1347-4820 |
| Popis: | BACKGROUND Warfarin reduces the risk of stroke in patients with atrial fibrillation, but requires a moderate-to-high time in therapeutic range (TTR). We hypothesized that point-of-care (POC) testing for prothrombin time-internationalized normalized ratio (PT-INR) could improve the TTR in patients receiving warfarin. METHODS AND RESULTS Eight outpatient clinics that introduced POC testing for PT-INR participated in this study. We identified 148 consecutive patients who received warfarin for at least 12 months before and after the introduction of POC testing. We compared the TTR before and after the introduction of POC testing for each patient. TTR after the introduction of POC testing was significantly higher than that beforehand (51.9%±33.0% vs. 69.3%±26.3%; P |
| Databáze: | OpenAIRE |
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