Effect of Sodium Monofluoroacetate on Multiplication of Eastern Equine Encephalomyelitis Virus
| Autor: | Louis P. Gebhardt, R. D. Higginbotham, T. Watanabe |
|---|---|
| Rok vydání: | 1952 |
| Předmět: |
Encephalomyelitis
Equine Infectivity Host (biology) Fluoroacetates Sodium Sodium monofluoroacetate Biology medicine.disease Virology General Biochemistry Genetics and Molecular Biology Virus In vitro chemistry.chemical_compound chemistry In vivo medicine Animals Encephalitis Virus Eastern Equine Horses Organic Chemicals Encephalomyelitis Sodium fluoroacetate Encephalitis |
| Zdroj: | Experimental Biology and Medicine. 80:758-761 |
| ISSN: | 1535-3699 1535-3702 |
| DOI: | 10.3181/00379727-80-19754 |
| Popis: | SummaryThe reduplication of Eastern equine encephalomyelitis virus in mouse brain is delayed in mice previously treated with sodium monofluoroacetate. This chemical seems to prolong the survival time of the infected animals, although it does not otherwise alter the course of infection. In high concentration, the chemical has no direct effect in vitro on the infectivity of the virus, nor does it show an in vivo effect on the susceptibility of the host to the infection with this virus. |
| Databáze: | OpenAIRE |
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