Pitfalls of Radiation Survey After Brachytherapy Implant Removal Preceding Tl-201 Study

Autor: Joseph F. Montebello, Cindy K. Parry, Jagadeesh R. Sonnad, Bhagwat D. Ahluwalia, Nina A. Mayr, George W. Macdurmon, Robert C. Gaston, Michael A. Gold, Charles D. Arnold
Rok vydání: 2002
Předmět:
Zdroj: Clinical Nuclear Medicine. 27:494-498
ISSN: 0363-9762
DOI: 10.1097/00003072-200207000-00006
Popis: An unexpected elevated postimplant radiation survey is described in an elderly patient with an interstitial low-dose-rate iridium-192 (Ir-192) needle implant for endometrial cancer. The elevated activity was related to prolonged clearance of Tl-201 from a cardiac study that had been performed 7 days earlier. The Tl-201 accumulated in the soft tissue, particularly the colon, resulting in increased survey readings over the abdomen and raising concern that an Ir-192 source remained within the patient. This case shows that delayed excretion of a diagnostic radionuclide agent can cause elevated activity high enough to confound postradiotherapy implant survey readings. The estimated surface exposure from a single iridium source left in the pelvis was determined using a phantom study. Possible factors causing decreased excretion of Tl-201 in a patient with heart disease, arteriosclerotic vascular disease, previous pelvic radiation therapy, and a brachytherapy procedure are discussed. A preloading radiation survey is recommended in patients who have had previous nuclear medicine studies involving radionuclides with long half-lives.
Databáze: OpenAIRE