CSN1S1 and CSN3 gene variants in female Murrah buffaloes in the Brazilian Amazon
| Autor: | NATALIA B.C. MEDEIROS, SÁVIO L.M. GUERREIRO, RAIRIANA S.R. PEREIRA, ANDRE L. SÁ, MARCOS RODRIGUES, RAFAEL MEZZOMO, RAYLON P. MACIEL, IGOR G. HAMOY, MARÍLIA D.N. RODRIGUES |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Anais da Academia Brasileira de Ciências v.94 suppl.3 2022 Anais da Academia Brasileira de Ciências Academia Brasileira de Ciências (ABC) instacron:ABC |
| Popis: | The characteristics of milk are controlled by several genes, with emphasis on the four genes from casein, CSN1S1; CSN1S2; CSN2 and CSN3, which are responsible encoding of fractions the milk protein. The study of genetic variants in these genes, seek to investigate alleles, insertions or deletions, that can directly reflect on productive characteristics, indicating differences in milk quality, composition and yield. The CSN1S1 and CSN3 genes were analyzed in lactating Murrah buffaloes using nucleotide sequencing. An SNP was found in the amplified fragment of the CSN1S1 gene, located in nucleotide number 2,123 of the promoter region in position nt-258 (A/G). As for the CSN3 gene, two SNPs of exon number 4 were identified in codons 33 (ACC/ATC) and 34 (ACC/ACT) of the analyzed fragment. This study contributes to important associations between genetic variants and the desired characteristics of milk and its derivatives in future studies, because the variants found may be associated with the quality of milk, enabling genetic selection to be assisted by molecular markers, indicating a major advance that makes it possible to select animals early. |
| Databáze: | OpenAIRE |
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