Isotropic 3D fast FLAIR imaging of the brain in multiple sclerosis patients: initial experience
| Autor: | Frederik Barkhof, Radu A. Manoliu, I. L. Tan, R.A. van Schijndel, P.J.W. Pouwels, H.J. Adèr |
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| Přispěvatelé: | Physics and medical technology, Radiology and nuclear medicine, Amsterdam Neuroscience - Brain Imaging, Amsterdam Neuroscience - Cellular & Molecular Mechanisms, Amsterdam Neuroscience - Neurodegeneration, Amsterdam Neuroscience - Neuroinfection & -inflammation, CCA - Cancer biology and immunology |
| Rok vydání: | 2002 |
| Předmět: |
Adult
Male medicine.medical_specialty Multiple Sclerosis Image registration Fluid-attenuated inversion recovery computer.software_genre White matter Voxel medicine Humans Radiology Nuclear Medicine and imaging Neuroradiology Echo-Planar Imaging business.industry Multiple sclerosis Ultrasound Subtraction Brain General Medicine Middle Aged Image Enhancement medicine.disease medicine.anatomical_structure Female Radiology business Nuclear medicine computer |
| Zdroj: | Tan, I L, Pouwels, P J W, van Schijndel, R A, Adèr, H J, Manoliu, R A & Barkhof, F 2002, ' Isotropic 3D fast FLAIR imaging of the brain in multiple sclerosis patients : Initial experience ', European Radiology, vol. 12, no. 3, pp. 559-567 . https://doi.org/10.1007/s00330-001-1170-8 European Radiology, 12(3), 559-567. Springer Verlag |
| ISSN: | 1432-1084 0938-7994 |
| DOI: | 10.1007/s00330-001-1170-8 |
| Popis: | The application of image registration and subtraction to detect change in multiple sclerosis (MS) disease burden on serial MR scans benefits from the use of isotropic voxels. An optimised 3D fast fluid-attenuated inversion recovery (FLAIR) sequence with 1.2- and 1.8-mm cubic voxels was compared with a 2D T2 SE sequence using standard 3-mm slices. Three-dimensional fast FLAIR and T2 SE series were obtained in 20 MS patients and 15 controls. Whole brain acquisition times for the 1.2- and 1.8-mm FLAIR were 21 and 10.5 min, respectively, for the interleaved T2 SE 16 min. Brain lesions were marked in consensus by two radiologists and the CNR was calculated in ten lesions. The mean number of lesions detected with the 1.2-mm FLAIR sequence was 115±76, compared with 85±59 for the T2 SE series (p |
| Databáze: | OpenAIRE |
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