Impact of an Anticaries Mouthrinse on In Vitro Remineralization and Microbial Control
| Autor: | Danette Ricci-Nittel, Gabrielle Kosmoski, Lauren Carratello, Robert J. Gambogi, Bruce R. Schemehorn, Jane Z. Zhang, Frank C. Sun, E. Eric Engelman, James A. McGuire |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Toothpaste
business.product_category Enamel paint biology Article Subject Biofilm Biofilm matrix Xylitol Antimicrobial biology.organism_classification Streptococcus mutans Microbiology lcsh:RK1-715 chemistry.chemical_compound chemistry lcsh:Dentistry visual_art visual_art.visual_art_medium business General Dentistry Fluoride Research Article |
| Zdroj: | International Journal of Dentistry International Journal of Dentistry, Vol 2014 (2014) |
| ISSN: | 1687-8728 |
| DOI: | 10.1155/2014/982071 |
| Popis: | Objective. The objective of this research was to evaluate the caries control potential of a new fluoride mouthrinse that also contained antimicrobial agents and a biofilm disrupting agent using differentin vitromodels.Methods. Fourin vitrostudies were conducted to assess the performance of this three pronged approach to caries control: (1) traditional enamel fluoride uptake, (2) surface microhardness study using pH cycling model and subsequent fluoride uptake, (3) a salivary biofilm flow-through study to determine the anti-microbial activity, and (4) a single species biofilm model measuring effect on biofilm matrix disruption.Results. The data showed that a LISTERINE rinse with fluoride, essential oils and xylitol was superior in promoting enamel fluoride uptake and in enhancing antimicrobial activity over traditional commercially available fluoridated products. An increase of the surface microhardness was observed when the LISTERINE rinse was used in combination with fluoridated toothpaste versus the fluoridated toothpaste alone. Finally, it was demonstrated that xylitol solutions disrupted and reduced the biovolume of biofilm matrix of matureStreptococcus mutans.Conclusion. Thesein vitrostudies demonstrated that a fluoride mouthrinse with antimicrobial agent and biofilm matrix disrupting agent provided multifaceted and enhanced anti-caries efficacy by promoting remineralization, reducing acidogenic bacteria and disrupting biofilm matrix. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text