Low, borderline and normal ankle-brachial index as a predictor of incidents outcomes in the Mediterranean based-population ARTPER cohort after 9 years follow-up
| Autor: | Rosa Forés, M. Teresa Alzamora, Guillem Pera, Marta Valverde, José Miguel Baena-Díez, Pere Torán |
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| Rok vydání: | 2019 |
| Předmět: |
Cardiovascular Procedures
Physiology Vascular Surgery Blood Pressure Coronary Disease 030204 cardiovascular system & hematology Pathology and Laboratory Medicine urologic and male genital diseases Vascular Medicine Biochemistry Cohort Studies Endocrinology 0302 clinical medicine Risk Factors Medicine and Health Sciences Coronary Heart Disease Prospective Studies 030212 general & internal medicine Prospective cohort study education.field_of_study Multidisciplinary Incidence Medical record Incidence (epidemiology) Lipids Hyperlipidemia Cholesterol Physiological Parameters Hypertension Cohort cardiovascular system Medicine Research Article Cohort study medicine.medical_specialty Endocrine Disorders Science Hypercholesterolemia Population Cardiology Surgical and Invasive Medical Procedures 03 medical and health sciences Signs and Symptoms Diagnostic Medicine Internal medicine Diabetes mellitus Diabetes Mellitus medicine Humans Ankle Brachial Index Obesity cardiovascular diseases education business.industry Body Weight Biology and Life Sciences medicine.disease body regions Metabolic Disorders business human activities Mace Follow-Up Studies |
| Zdroj: | PLoS ONE r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol instname Dipòsit Digital de Documents de la UAB Universitat Autònoma de Barcelona PLoS ONE, Vol 14, Iss 1, p e0209163 (2019) |
| ISSN: | 1932-6203 |
| Popis: | Background Guidelines recommended adopting the same cardiovascular risk modification strategies used for coronary disease in case of low Ankle-brachial index (ABI), but here exist few studies on long-term cardiovascular outcomes in patients with borderline ABI and even fewer on the general population. Aim The aim of the present study was to analyze the relationship between long-term cardiovascular events and low, borderline and normal ABI after a 9-year follow up of a Mediterranean population with low cardiovascular risk. Design and setting A population-based prospective cohort study was performed in the province of Barcelona, Spain. Method A total of 3,786 subjects >49 years were recruited from 2006-2008. Baseline ABI was 1.08 +/- 0.16. Subjects were followed from the time of enrollment to the end of follow-up in 2016 via phone calls every 6 months, systematic reviews of primary-care and hospital medical records and analysis of the SIDIAP (Information System for Primary Care Research) database to confirm the possible appearance of cardiovascular events. Results 3146 individuals participated in the study. 2,420 (77%) subjects had normal ABI, 524 (17%) had borderline ABI, and 202 (6.4%) had low ABI. In comparison with normal and borderline subjects, patients with lower ABI had more comorbidities, such as hypertension, hypercholesterolemia and diabetes. Cumulative MACE incidence at 9 years was 20% in patients with low ABI, 6% in borderline ABI and 5% in normal ABI. The annual MACE incidence after 9 years follow-up was significantly higher in people with low ABI (26.9/1000py) (p |
| Databáze: | OpenAIRE |
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