Comparação entre anestesia total intravenosa com propofol e bolus intermitente de tiletamina-zolazepam em macaco-prego (Sapajus apella)
| Autor: | Ricardo Guilherme D´Otaviano de Castro Vilani, Paulo Henrique Gomes de Castro, José Carlos Muniz, Rafaela Galante, Dorli S. Amora Júnior, Vanessa Nadine Gris, Elizabeth R. Carvalho |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
tiletamine-zolazepam
bolus intermitente clinics 040301 veterinary sciences Anestesia total intravenosa Macaco-prego primate Sapajus paella Propofol / uso terap?utico 0403 veterinary science TIVA 03 medical and health sciences recovery Bolus (medicine) Adjuvantes Anest?sicos refinamento Medicine refinement Adverse effect Primatas / anatomia & histologia 030304 developmental biology 0303 health sciences lcsh:Veterinary medicine General Veterinary propofol business.industry Intravenous anesthesia 04 agricultural and veterinary sciences Anest?sicos Intravenosos / uso terap?utico intermittent bolus recuperação primata clínica tiletamina-zolazepam Sapajus apella Anestesia / utiliza??o Anesthesia capuchin monkey Sapajus apela Anesthetic Intermittent bolus Midazolam Arterial blood lcsh:SF600-1100 business Propofol medicine.drug |
| Zdroj: | Pesquisa Veterinária Brasileira, Vol 39, Iss 4, Pp 271-277 (2019) Repositório Digital do Instituto Evandro Chagas (Patuá) Instituto Evandro Chagas (IEC) instacron:IEC Pesquisa Veterinária Brasileira, Volume: 39, Issue: 4, Pages: 271-277, Published: 02 MAY 2019 Pesquisa Veterinária Brasileira v.39 n.4 2019 Pesquisa Veterinária Brasileira Colégio Brasileiro de Patologia Animal (CBPA) instacron:EMBRAPA |
| ISSN: | 1678-5150 |
| Popis: | Dissociative anesthesia results in stressful and long recovery periods in monkeys and use of injectable anesthetics in medical research has to be refined. Propofol has promoted more pleasure wake up from anesthesia. The objectives of this study were to investigate the use of intravenous anesthetic propofol, establishing the required infusion rate to maintain surgical anesthetic level and comparing it to tiletamine-zolazepam anesthesia in Sapajus apella. Eight healthy capuchin monkeys, premedicated with midazolam and meperidine, were anesthetized with propofol (PRO) or tiletamine-zolazepam (TZ) during 60 minutes. Propofol was infused continually and rate was titrated to effect and tiletamine-zolazepam was given at 5mg/kg IV bolus initially and repeated at 2.5mg/kg IV bolus as required. Cardiopulmonary parameters, arterial blood gases, cortisol, lactate and quality and times to recovery were determined. Recovery quality was superior in PRO. Ventral recumbency (PRO = 43.0±21.4 vs TZ = 219.3±139.7 min) and normal ambulation (PRO = 93±27.1 vs TZ = 493.7±47.8 min) were faster in PRO (p |
| Databáze: | OpenAIRE |
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