Nutrient dietary patterns and gastric cancer risk in Italy
| Autor: | Valeria Edefonti, Paola Bertuccio, Eva Negri, Claudio Pelucchi, Adriano Decarli, Carlo La Vecchia, Francesca Bravi, Monica Ferraroni |
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| Přispěvatelé: | Bertuccio P, Edefonti V, Bravi F, Ferraroni M, Pelucchi C, Negri E, Decarli A, La Vecchia C, P. Bertuccio, V.C. Edefonti, F. Bravi, M. Ferraroni, C. Pelucchi, E. Negri, A. Decarli, C. La Vecchia |
| Rok vydání: | 2009 |
| Předmět: |
Adult
Male medicine.medical_specialty Epidemiology Gastroenterology Risk Assessment Young Adult Stomach Neoplasms Internal medicine Vegetables medicine Humans Risk factor Stomach cancer Aged Aged 80 and over business.industry Stomach Case-control study Cancer Starch Odds ratio Feeding Behavior Middle Aged medicine.disease Prognosis Dietary Fats Diet medicine.anatomical_structure Oncology Quartile Italy Case-Control Studies Fruit Female Risk assessment business |
| Zdroj: | Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 18(11) |
| ISSN: | 1538-7755 |
| Popis: | Background: There have been several studies on diet and gastric cancer, but only a few investigations have considered the role of dietary patterns. Methods: We investigated gastric cancer risk in relation to dietary patterns in a case-control study conducted in northern Italy between 1997 and 2007, including 230 patients with incident, histologically confirmed gastric cancer and 547 frequency-matched controls, admitted to the same hospitals as cases, with acute nonneoplastic conditions. Dietary habits were investigated through a validated food frequency questionnaire including 78 foods and beverages. We identified a posteriori dietary patterns on a selected set of 28 micro- and macro-nutrients through an exploratory principal component factor analysis. We estimated the odds ratios (OR) and the corresponding 95% confidence intervals (95% CI) using conditional logistic regression models on quartiles of factor scores. Results: We identified four major dietary patterns, named “animal products”, “vitamins and fiber”, “vegetable unsaturated fatty acids”, and “starch-rich”. We observed a positive association between gastric cancer risk and the “animal products” (OR, 2.13; 95% CI, 1.34-3.40, for the highest versus the lowest score quartile) and the “starch-rich” (OR, 1.67; 95% CI, 1.01-2.77) dietary patterns. The “vitamins and fiber” pattern (OR, 0.60; 95% CI, 0.37-0.99) was inversely associated with gastric cancer, whereas no significant association emerged with the “vegetable unsaturated fatty acids” pattern (OR, 0.89; 95% CI, 0.56-1.42). Conclusions: Our analysis suggests a protective effect against gastric cancer risk of dietary patterns rich in fruits and vegetables, and a positive association of dietary patterns rich in meats and animal fats and starchy foods. (Cancer Epidemiol Biomarkers Prev 2009;18(11):2882–6) |
| Databáze: | OpenAIRE |
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