Pattern electroretinogram recorded by skin electrodes in early ocular hypertension and glaucoma
| Autor: | Martin Štrucl, Branka Stirn-Kranjc, Marko Hawlina, Jelka Brecelj, Žare Finderle |
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| Rok vydání: | 1989 |
| Předmět: |
Adult
Male medicine.medical_specialty genetic structures Eye disease Visual Acuity Ocular hypertension Glaucoma Retinal ganglion chemistry.chemical_compound Predictive Value of Tests Physiology (medical) Ophthalmology Electroretinography Humans Medicine Intraocular Pressure Aged medicine.diagnostic_test business.industry Retinal Galvanic Skin Response Middle Aged medicine.disease eye diseases Sensory Systems Ganglion Visual field Form Perception medicine.anatomical_structure Pattern Recognition Visual chemistry Visual Field Tests Female Ocular Hypertension sense organs Visual Fields business Glaucoma Open-Angle |
| Zdroj: | Documenta Ophthalmologica. 73:183-191 |
| ISSN: | 1573-2622 0012-4486 |
| DOI: | 10.1007/bf00155036 |
| Popis: | Diagnostic value of transient pattern electroretinogram (PERG), recorded by skin electrodes, was compared with Goldmann perimetry in cases of ocular hypertension and glaucoma. According to the assumption that the PERG mostly reflects activity of the retinal glanglion cells, and histological evidence that 30–50% atrophy of the retinal ganglion cells is necessary to cause defects in visual field, we wanted to assess if i) this method could be more sensitive in detecting early glaucomatous damage than routine Goldmann perimetry in eyes with normal or only borderline elevated intraocular pressure in the time of PERG recording (first group of patients), and ii) how the PERG amplitude corresponds to ganglion cell loss, expected in the eyes with already detectable initial glaucomatous visual field defects, according to Goldmann II/2 isopter, with normal or borderline elevated intraocular pressure in the time of PERG recording (second group). In the group with no visual field defects subnormal amplitude of the major positive component of the PERG, N1-P1, was detected in three of 30 eyes (10%), while in the group with initial visual field defects N1-P1 amplitude was subnormal in 6 of 11 eyes (54%). The amplitude of the major negative PERG component, P1-N2, was found normal in all eyes of the first group and subnormal in 5 eyes (45%) of the second group. |
| Databáze: | OpenAIRE |
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