Oral lesions containing amyloid-like material
| Autor: | Ramiro Alejandro Tomasi, Liam Robinson, Felipe Paiva Fonseca, Willie F. P. van Heerden, Ricardo Santiago Gomez, Hélder Antônio Rebelo Pontes, Pablo Agustin Vargas, Raghu Radhakrishnan, Ömer Günhan, Maria Goretti Freire de Carvalho, Keith D. Hunter, Faizan Alawi, Maria Sissa Pereira Sant'Ana, Carla Isabelly Rodrigues-Fernandes, Cinthia Veronica Bardález López de Cáceres, Oslei Paes de Almeida, Ciro Dantas Soares |
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| Rok vydání: | 2020 |
| Předmět: |
Pathology
medicine.medical_specialty Amyloid Odontogenic Tumors Degeneration (medical) Pathology and Forensic Medicine 03 medical and health sciences 0302 clinical medicine Eosinophilic Oral and maxillofacial pathology medicine Humans Radiology Nuclear Medicine and imaging Dentistry (miscellaneous) Amyloid like business.industry Amyloidosis 030206 dentistry medicine.disease Elastic Tissue medicine.anatomical_structure 030220 oncology & carcinogenesis Immunohistochemistry Surgery Oral Surgery business Amyloid (mycology) Elastic fiber |
| Zdroj: | Oral surgery, oral medicine, oral pathology and oral radiology. 132(2) |
| ISSN: | 2212-4411 |
| Popis: | During oral pathology daily practice, true amyloid may be identified in oral amyloidosis and several odontogenic tumors. However, histologic examination often reveals other oral and perioral diseases with similar eosinophilic, acellular, amorphous substances. These include extensive areas of collagenous sclerosis, fibrin deposition, elastic fiber degeneration, and dentinoid material, which may resemble amyloid under light microscopic examination. These materials are often termed "amyloid-like" due to their close histologic resemblance to true amyloid. The rarity of most of these conditions and their strong histologic similarity may hamper an accurate diagnosis. Definitive diagnosis of these lesions may require clinical correlation; laboratory evaluation; histochemical or immunohistochemical reactions; and, in some cases, genetic investigation. In this review, we describe the main clinicopathologic features of this group of diseases that may manifest in the oral and/or perioral regions and that have in common the presence of amyloid-like material deposition. |
| Databáze: | OpenAIRE |
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