Anaphylaxis after rabies vaccination for dogs in Japan
| Autor: | Keijiro Mizukami, Masaharu Hisasue, Keigo Kurata, Masaki Ochiai, Ichiro Imanishi, Tadahiro Nasukawa, Megumi Yoshida, Jumpei Uchiyama, Masato Itoh, Masahiro Sakaguchi, Hajime Tsujimoto |
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| Rok vydání: | 2021 |
| Předmět: |
Veterinary medicine
Rabies adverse reaction Rabies vaccination Rabies vaccine Dogs Japan medicine Internal Medicine anaphylaxis Animals Dog Diseases Adverse effect General Veterinary business.industry Vaccination medicine.disease Note rabies vaccine Rabies Vaccines dog Christian ministry business Anaphylaxis medicine.drug |
| Zdroj: | The Journal of Veterinary Medical Science |
| ISSN: | 1347-7439 |
| Popis: | Severe adverse reactions after rabies vaccination in dogs were examined from 317 cases reported to the Ministry of Agriculture, Forestry and Fisheries (MAFF) in Japan during 15-year period from April 2004 to March 2019. We found that 109 of the 317 dogs showed anaphylaxis (0.15/100,000 vaccinated dogs), and 71 of the 109 cases of anaphylaxis resulted in death (0.10/100,000 vaccinated dogs). We measured bovine serum albumin (BSA) in four commercially available rabies vaccines and found the levels ranged from 0.1 to 16.6 µg/dose. Our survey showed that the rate of anaphylaxis to rabies vaccines in dogs is rare, although some cases of anaphylaxis resulted in death. Veterinarians should be well prepared to deal with vaccine-associated anaphylaxis. |
| Databáze: | OpenAIRE |
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