Aqueous Extract of Valerian Reduces Latency to Fall Asleep in Man
Autor: | P. D. Leathwood, F. Chauffard |
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Rok vydání: | 1985 |
Předmět: |
Adult
Male Valerian Time Factors medicine.drug_class Pharmaceutical Science Placebo Analytical Chemistry Hypnotic Double-Blind Method Drug Discovery Insomnia medicine Humans Latency (engineering) Volunteer Pharmacology Plants Medicinal biology Plant Extracts business.industry Organic Chemistry Repeated measures design Middle Aged biology.organism_classification Complementary and alternative medicine Anesthesia Molecular Medicine Female medicine.symptom Sleep onset Sleep business |
Zdroj: | Planta Medica. 51:144-148 |
ISSN: | 1439-0221 0032-0943 |
DOI: | 10.1055/s-2007-969430 |
Popis: | A group of 8 volunteers suffering from mild insomnia received a placebo, 450 mg or 900 mg of an aqueous extract of valerian root in a double-blind, repeated measures, random-order design. Subjective sleep ratings were assessed by questionnaire and movements were recorded throughout the night with wrist-worn activity meters. Using the first period of 5 consecutive minutes without movement as a criterion of sleep onset, there was a significant decrease in sleep latency with 450 mg valerian compared to placebo (15.8 ± 2.2 min vs 9.0 ± 1.5 min; paired “t” = 3.37;p < 0.01). The higher dose of valerian produced no further improvement in sleep latency. |
Databáze: | OpenAIRE |
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