Effects of Prolonged Cortisone Therapy on the Statural Growth, Skeletal Maturation and Metabolic Status of Children

Autor:	D Iezzoni, L Burgin, D Gribetz, N B Talbot, F M Blodgett
Rok vydání:	1956
Předmět:	medicine.medical_specialty Allergy business.industry Growth General Medicine medicine.disease Symptomatic relief Bone and Bones Cortisone Metabolism Endocrinology Skeletal maturation Internal medicine medicine Humans Child business Hormone medicine.drug
Zdroj:	New England Journal of Medicine. 254:636-641
ISSN:	1533-4406 0028-4793
DOI:	10.1056/nejm195604052541402
Popis:	OBSERVATIONS on children suffering from Cushing's syndrome have indicated clearly that adrenocortical steroids of the cortisone type may have a marked tendency to suppress growth.1 , 2 The present study was undertaken, therefore, when it became apparent that the symptomatic relief afforded patients by cortisone might result in the prolonged administration of this hormone to growing children. The chief purpose of the study has been to determine if possible what effect long-continued cortisone therapy might be expected to have on ultimate stature and metabolic status. Material and Methods The patients studied were children receiving cortisone because of adrenocortical virilism, panhypopituitarism, hypoadrenocorticism or . . .
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5009130bf21391b59deb4429af683da https://doi.org/10.1056/nejm195604052541402 Zobrazit plný text záznamu