Comparison of some secondary metabolite content in the seventeen species of the Boraginaceae family

Autor:	Małgorzata Wójcik, Sławomir Dresler, Grałzyna Szymczak
Rok vydání:	2017
Předmět:	rosmarinic acid Cynoglossum Anchusa azurea Phytochemicals capillary electrophoresis Pharmaceutical Science allantoin 01 natural sciences Drug Discovery Pulmonaria Botany Pharmacology Nonea shikonin Cynoglossum creticum biology 010405 organic chemistry Plant Extracts rutin lcsh:RM1-950 Electrophoresis Capillary General Medicine Boraginaceae biology.organism_classification chemometrics Echium vulgare 0104 chemical sciences 010404 medicinal & biomolecular chemistry lcsh:Therapeutics. Pharmacology Complementary and alternative medicine Molecular Medicine Echium italicum
Zdroj:	Pharmaceutical Biology, Vol 55, Iss 1, Pp 691-695 (2017)
ISSN:	1744-5116
Popis:	Context: The Boraginaceae family comprises plants that have important therapeutic and cosmetic applications. Their pharmacological effect is related to the presence of naphthaquinones, flavonoids, terpenoids, phenols, or purine derivative – allantoin. Objective: In the present study, comparison of some secondary metabolite content and phytochemical relationship between 17 species of the Boraginaceae family were analyzed. Materials and methods: High performance capillary electrophoresis (HPCE) was used to perform a chemometric analysis in the following Boraginaceae species: Anchusa azurea Mill., Anchusa undulata L., Borago officinalis L., Buglossoides purpurocaerulea (L.) I.M. Johnst., Cerinthe minor L., Cynoglossum creticum Mill, Echium italicum L., Echium russicum J.F. Gmel., Echium vulgare L., Lindelofia macrostyla (Bunge) Popov (syn. Lindelofia anchusoides (Lindl.) Lehm.), Lithospermum officinale L., Nonea lutea (Desr.) DC., Omphalodes verna Moench (syn. Cynoglossum omphaloides L.), Pulmonaria mollis Wulfen ex Hornem., Pulmonaria obscura Dumort., Symphytum cordatum Waldst. & Kit ex Willd., and Symphytum officinale L. Results: Six active compounds in shoot extracts (allantoin, p-hydroxybenzoic acid, rutin, hydrocaffeic acid, rosmarinic acid, and chlorogenic acid) and four compounds in root extracts (allantoin, hydrocaffeic acid, rosmarinic acid, and shikonin) were identified. The presence and abundance of these compounds were used for the characterization of the species and for revealing their phytochemical similarity and differentiation. Discussion and conclusion: The present study provides the first comprehensive report of the extraction and quantification of several compounds in Boraginaceae species (some of them for the first time). Among the 17 species studied, species with potentially high pharmacological activity were recognized.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4f27ecf8583913a3dfc66482e2e5428 https://pubmed.ncbi.nlm.nih.gov/28140740 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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