Liver Transplant in Hemoglobin SC Disease and Autoimmune Hepatitis: A Case Report

Autor: Kim, Ahyoung, Assarzadegan, Naziheh, Anders, Robert A., Oshima, Kiyoko, Chaturvedi, Shruti, Weeks, Sharon, Kohli, Ruhail, Lanzkron, Sophie, Gurakar, Ahmet, Garonzik-Wang, Jacqueline, Chen, Po-Hung
Rok vydání: 2022
Předmět:
Zdroj: Exp Clin Transplant
ISSN: 2146-8427
1304-0855
Popis: While liver transplantation (LT) is a life-saving measure for individuals with end-stage liver disease, the peri-operative management may be challenging in individuals with concomitant sickle cell disease (SCD). We report a case of a 50-year-old man with SCD genotype SC (HbSC) and cirrhosis secondary to autoimmune hepatitis (AIH) who underwent LT. His post-operative course included upper extremity deep vein thrombosis (DVT), pulmonary embolus (PE), stroke via a patent foramen ovale after a line removal, and posterior reversible encephalopathy syndrome (PRES). Fortunately, he is alive with a functioning graft at 10 months after LT. This case highlights the feasibility of LT in SCD given the support of meticulous multidisciplinary care and the unique aspects of AIH and SCD for LT consideration. .
Databáze: OpenAIRE