Characterization of Implanted Stents through Neointimal Tissue Bioimpedance Simulations
| Autor: | Juan Alfonso Serrano, Alberto Olmo, J. M. Portillo-Anaya, Alberto Yufera, Pablo Pérez, Andrés Maldonado-Jacobi, Gloria Huertas |
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| Rok vydání: | 2020 |
| Předmět: |
Materials science
Simulation test medicine.medical_treatment 0206 medical engineering Lumen (anatomy) Stent 02 engineering and technology Light hole 030204 cardiovascular system & hematology medicine.disease 020601 biomedical engineering Coronary Restenosis 03 medical and health sciences 0302 clinical medicine Restenosis Neointima medicine Electric Impedance Humans Stents Biomarkers Biomedical engineering |
| Zdroj: | EMBC |
| ISSN: | 2694-0604 |
| Popis: | This work describes how is possible the definition of the light hole or lumen in implanted stents affected by restenosis processes using the BioImpedance (BI) as biomarker. The main approach is based on the fact that neointimal tissues implied in restenosis can be detected and measured thanks to their respective conductivity and dielectric properties. For this goal, it is proposed a four-electrode setup for bioimpedance measurement. The influence of the several involved tissues in restenosis: fat, muscle, fiber, endothelium and blood, have been studied at several frequencies, validating the setup and illustrating the sensitivity of each one. Finally, a real example using a standard stent, has been analyzed for stable and vulnerable plaques in restenosis test cases, demonstrating that the proposed method is useful for the stent obstruction test. Bioimpedance simulation test has been performed using the electric physics module in COMSOL Multiphysics®. |
| Databáze: | OpenAIRE |
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