THE EXCRETION OF SODIUM 6-(2,6-DIMETHOXYBENZ-AMIDOPENICILLANATE) MONOHYDRATE IN RATS

Autor:	Jean A. White, G. T. Stewart, Patricia M. Harrison
Rok vydání:	1960
Předmět:	Ions medicine.medical_specialty Chemistry Sodium Penicillin metabolism chemistry.chemical_element Penicillins Articles General Medicine Urine digestive system Body Fluids Rats Excretion Feces Endocrinology Internal medicine medicine Animals Bile
Zdroj:	British Journal of Pharmacology and Chemotherapy. 15:571-573
ISSN:	0366-0826
DOI:	10.1111/j.1476-5381.1960.tb00284.x
Popis:	The excretion of sodium 6-(2:6 dimethoxybenzamido) penicillanate monohydrate has been studied. When injected intramuscularly it was rapidly excreted in the bile and urine of rats, but only in trace amounts in the faeces. The excretion products in the bile (2 to 3% of the dose) and urine (26-84% of the dose) are microbiologically active. The product in the bile may be in conjugated form.
Databáze:	OpenAIRE
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